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Patanol Eye Drops 0.1%

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Description

Patanol (olopatadine) is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of itching or watery eyes.

Patanol eye drops are used to treat itching, burning, redness, watering, and other eye symptoms caused by allergic conditions.

Patanol may also be used for purposes not listed in this medication guide.

Important information

Before using Patanol, tell your doctor if you have any type of infection in your eye.

Do not use Patanol while you are wearing contact lenses. The eyes drops may contain a preservative that can be absorbed by soft contact lenses. Wait at least 10 minutes after using Patanol before putting your contact lenses in.

Avoid wearing contact lenses while your eyes are red or irritated.

Do not allow the Patanol dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

Stop using Patanol and call your doctor at once if you have severe redness, swelling, burning, stinging, drainage, crusting, or other irritation when using the eye drops.

Before taking this medicine

You should not use Patanol if you are allergic to olopatadine.

To make sure Patanol is safe for you, tell your doctor if you have any type of infection in your eye.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether olopatadine ophthalmic passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use Patanol?

Use Patanol exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Wash your hands before using the eye drops.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
  • Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
  • Use only the number of drops your doctor has prescribed.
  • Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the Patanol eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Store Patanol eye drops at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

Patanol dosing information

Usual Adult Dose of Patanol for Seasonal Allergic Conjunctivitis:

Ophthalmic solution 0.1%: Instill one drop in each affected eye two times a day at a 6 to 8 hour interval.

Ophthalmic solution 0.2%: Instill one drop in each affected eye once a day.

Usual Pediatric Dose of Patanol for Seasonal Allergic Conjunctivitis:

2 years or younger: Safety and effectiveness have not been established.

3 to 18 years:
Ophthalmic 0.1% solution: Instill one drop in each affected eye two times a day at a 6 to 8 hour interval.
Ophthalmic 0.2% solution: Instill one drop in each affected eye once a day.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What should I avoid while using Patanol?

Do not use this medicine while wearing contact lenses. Patanol eye drops may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

Avoid wearing contact lenses while your eyes are red or irritated.

Avoid using other eye medications not prescribed by your doctor.

Patanol side effects

Get emergency medical help if you have signs of an allergic reaction to Patanol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe burning, stinging, or irritation after using this medicine; or
  • eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection).

Common Patanol side effects may include:

  • dry eyes;
  • blurred vision;
  • mild eye irritation;
  • feeling like something is in your eye;
  • puffy eyelids; or
  • unusual or unpleasant taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor or our pharmacist for medical advice about side effects.

What other drugs will affect Patanol?

It is not likely that other drugs you take orally or inject will have an effect on olopatadine used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Patanol only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

WARNINGS

PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% is for topical use only and not for injection or oral use.

PRECAUTIONS

Carcinogenesis, Mutagenesis, Impairment of Fertility: Olopatadine administered orally was not carcinogenic in mice and rats in doses up to 500 mg/kg/day and 200 mg/kg/day, respectively. Based on a 40 µL drop size, these doses were 78,125 and 31,250 times higher than the maximum recommended ocular human dose (MROHD). No mutagenic potential was observed when olopatadine was tested in an in vitro bacterial reverse mutation (Ames) test, an in vitro mammalian chromosome aberration assay or an in vivo mouse micronucleus test. Olopatadine administered to male and female rats at oral doses of 62,500 times MROHD level resulted in a slight decrease in the fertility index and reduced implantation rate; no effects on reproductive function were observed at doses of 7,800 times the maximum recommended ocular human use level.

Pregnancy: Pregnancy Category C. Olopatadine was found not to be teratogenic in rats and rabbits. However, rats treated at 600 mg/kg/day, or 93,750 times the MROHD and rabbits treated at 400 mg/kg/day, or 62,500 times the MROHD, during organogenesis showed a decrease in live fetuses. There are, however, no adequate and well controlled studies in pregnant women. Because animal studies are not always predictive of human responses, this drug should be used in pregnant women only if the potential benefit to the mother justifies the potential risk to the embryo or fetus.

Nursing Mothers: Olopatadine has been identified in the milk of nursing rats following oral administration. It is not known whether topical ocular administration could result in sufficient systemic absorption to produce detectable quantities in the human breast milk. Nevertheless, caution should be exercised when PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% is administered to a nursing mother.

Pediatric Use: Safety and effectiveness in pediatric patients below the age of 3 years have not been established.

Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients.